Discovering how evolution impacts neuronal function to create new behaviors
Sensory systems must filter and respond to the vast array of signals being produced in an
environment. An incorrect response from these signals could make finding a meal more
difficult, or worse, becoming a meal for someone else! In past and current work, we have
found that cavefish are the only known fish population that exhibits negative
photokinesis, in contrast to the highly conserved positive photokinesis observed in other
fish species. By utilizing modern genetic and neurocomputational techniques in the lab,
we were able to investigate the brain regions and neurons that cause changes in
photokinesis behavior. We are now actively investigating both the genetic causes of this
behavioral change and the molecular identity of the neurons that contribute to the
photokinesis circuit. In addition, we are currently screening other sensory systems and
building new projects to understand how sensory integration across systems can evolve!